Remineralizing Efficacy of Chitosan-Based Nanomaterials on Artificially Induced Incipient Carious Lesions.

Introduction:The demineralization of dental hard tissues is still an issue of increasing concern.White spot lesions (WSL) are the earliest sign of dental caries.The management of white spot lesions (WSL) requires non-invasive approaches such as fluoride and non-fluoride remineralization systems or sealing with resin‐based materials.Aim of the wok: Assessment of the remineralizing efficacy of Bioactive glass-chitosan and Hydroxy Apatite-Chitosan on artificial white spot lesions. Materials and methods:Sixty extracted human permanent teeth were selected for the study.Specimens were divided into four groups: group 1: fluoride varnish (voco), group 2: Bioactive Glass-Chitosan varnish (nano gate company), group 3: Hydroxy Apatite-Chitosan varnish (nano gate company), group 4: control (treated with remineralizing solution). Artificial carious lesions were induced in all the specimensand treated with respective varnishes twice daily for 7 days. The Diagnodent reading was taken, and the surface characteristics of the enamel specimens were evaluated by SEM at baseline, after demineralization and after remineralization. Results: SEM evaluationshowed favourable surface changes in all the fourstudy groups after remineralization therapy.Intragroup comparison of DIAGNOdent readings showed a highly significantdifference between baseline,postdemineralization,and postremineralization values. However,the intergroup comparison was statisticallynonsignificant.Conclusion: All test agents werecomparable in their remineralization potential